Green synthesis of zinc oxide nanoparticles and their application in controlled drug release


Abstract:
Green synthesis of zinc oxide (ZnO) nanoparticles using the leaves of Catharanthus roseus has been reported in this research work. ZnO nanoparticles tend to aggregate easily, therefore for maintaining their stability and reducing their toxicity, poly vinyl pyrrolidone (PVP) was experimented as stabilising and coating agent. These coated nanoparticles were further used for the controlled release of Quercetin, a potential anticancer and anti-inflammatory drug. The size of the nanoparticles was found to be 4 nm and the coating of PVP was confirmed by FTIR analysis. Drug release profile has shown a good sustained release of Quercetin.

Keywords:
Zinc oxide nanoparticle; Catharanthus roseus; Green synthesis; Poly vinyl pyrrolidone (PVP); Quercetin; FTIR analysis.

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How to cite this article:
Prashanth K, Baskar V, Madhan R . Green synthesis of zinc oxide nanoparticles and their application in controlled drug release. Journal of Biological and Information Sciences. 2014. 3 (3). 12-14.
Available from: http://archive.biolim.org/jbis/read/BOJ001A0025.