Skin ageing

Skin ageing
Skin ageing is a process that happens in all the human beings. It happens due to intrinsic and extrinsic factors. Intrinsic factors (such as hormones, genetics, etc.) result in chronological ageing (that happens naturally) and extrinsic factors (such as ultraviolet radiation) result in photo-ageing (premature ageing due to UV radiation exposure). Our skin has three layers, namely hypodermis, dermis and subcutaneous layer. The dermis layer provides elasticity and protects the body from injuries. Fibroblasts produced in the dermis layer are actively synthesising elastic fibres and collagens. Infants usually have small collagen bundles; whereas, adults have thicker bundles of collagen. These collagens are main connective tissues found in the skin. Normally 15 distinct types of collagens are present in our body, which are located in tendons, and the lining of bones and dermis. Collagen is the major stress resistant of the skin. Collagen represents 70% of our skin. Generally, mitochondria have oxidants and anti-oxidants, which are in a balanced state; this results in the production of reactive oxygen species when our skin is exposed to UV. Water gets converted to hydrogen peroxide instead of oxygen that causes imbalanced state in oxidants and anti-oxidants level. Therefore, when our skin is exposed to UV radiation, the reactive oxygen species produced lead to the synthesis of matrix metalloproteinases, which aid in regulation of activator protein (AP1) that results in the degradation of extracellular matrix. This continuous exposure results in solar scars, which result in skin ageing. The increase in reactive oxygen species also causes DNA damage.

Prevent skin ageing by adding phytochemicals rich fruits and vegetables in your diet!!!
How to cite this article:
Veronica Grite S. Skin ageing. BioLim O-Media. 20 , 5-22. 1(2).
Available from: http://archive.biolim.org/omedia/read/BOMA0029.