Forensic bioinformatics: a milestone in forensic medical diagnosis

Forensic bioinformatics: a milestone in forensic medical diagnosis
Forensic bioinformatics is a branch of bioinformatics which came into light during 11th September 2001 terrorists’ attacks in USA. This brought up a solution for a major unprecedented problem of forensic DNA matching and data handling technique, in identifying vast human remains, which were fully crushed in the attacks. Forensic bioinformatics acts as an important link between statistics and computer science by bringing them together to bear problems in biology and law. The areas where forensic bioinformatics is currently focused include mass disaster identification, gender determination, DNA evidencing and preparation of DNA case, familial search and interpretation of mixed DNA samples, sequence unmasking, DNA typing and profile statistics, analysis of STR (short tandem repeats) and VNTR (variable number tandem repeats profiles), computer review and storing DNA evidence. Many softwares and databases that are useful in forensic bioinformatics for haplotype scoring, selection and visualization have been developed. Haploview, Haplofreq, Tagger, GOLD (graphical display of linkage disequilibrium), SNP tagger, PHASE, PLINK, Snphap, Arlequin, Hapassoc and STR databases are few softwares/databases, which are currently used for forensic bioinformatics. Further research and development in forensic bioinformatics sector would proliferate our dealing with genes, which could set new boundaries for the current limits.
How to cite this article:
Deepa Mary Stanly. Forensic bioinformatics: a milestone in forensic medical diagnosis. BioLim O-Media. 07 July, 2015. 3(6).
Available from: http://archive.biolim.org/omedia/read/BOMA0082.