DNA sequencing: now at our finger tips

DNA sequencing: now at our finger tips

When we hear the word DNA sequencers, the first thing that comes to our mind is a huge instrument with high speed processors and complicated steps that could lead automated DNA sequencing. But this whole picture was changed by Oxford Nanopores when they started shipping their early versions of MinION DNA sequencers to few selected laboratories. The MinION sequencer is a device, which is used for DNA sequencing comprising a proprietary sensor chip, application-specific integrated circuit (ASIC) and nanopores. This four inches in length device is used to perform a complete single-molecule sensing experiment by just plugging it directly into a laptop or desktop computer through a USB port which in return delivers real-time experimental data. The MinION does its operation through MinKNOW software while the users perform their operations through a cloud system that would be enabled to do locally in the near future. The device has given emphasis on delivering the simplest possible sample preparation and workflows. The device at present is focusing on being compatible with complex samples (blood or serum) and environmental samples (water samples).


How to cite this article:
Deepa Mary Stanly. DNA sequencing: now at our finger tips. BioLim O-Media. 22 July, 2015. 3(6).
Available from: http://archive.biolim.org/omedia/read/BOMA0085.