Glutathione – a master antioxidant and an immune system modulator


The free radicals (oxidants) produced during cellular metabolism result in toxic effects that involve majority of diseases related to ageing, such as Alzheimer's, cataract, Parkinson's, arthritis, etc. which are inevitable. In contrast to age-related diseases, they also result in the destruction of DNA, clogging of arteries, etc. that can be prevented. In general, no individual is free from oxidative stress, as it is either the result of one's own cellular metabolism or the exposure to environmental toxins (such as air, food and water pollution). Hence, to combat these harmful unstable molecules, the body requires antioxidants of different varieties because each antioxidant targets certain type of damaging free radical. Each antioxidant does its own job in the body, and some even work together. One such antioxidant is Glutathione that provides greater antioxidant protection and recharges other antioxidants also within the body. Glutathione is termed as a master antioxidant by scientists, as it possesses the ability to maintain the exogenous antioxidants, such as vitamin C and E in their active form. Also, it plays a significant role in immune function. The biochemical reduction-oxidation state of Glutathione within our bodies is one of the best gauges of oxidative stress levels and overall health. Glutathione's deficiency is believed to lead almost every single disease, since it has its existence in every cell of the body. About such a special peptide molecule this review is, which represents its importance in human health apart from depicting its dietary sources and other beneficial aspects elaborately.

Glutathione; Antioxidant; Immunity; GSH; GSSG; Ageing

Full text PDF | Download PDF

How to cite this article:
Dhivya H. Glutathione – a master antioxidant and an immune system modulator. Journal of Biological and Information Sciences. 2012. 1 (3). 33-35.
Available from: